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July 17th, 2015

Repairing mitochondrial disease

By Amy Olson

A multidisciplinary team has successfully eliminated fatal mitochondrial DNA mutations in stem cells from patients with mitochondrial diseases. The study is published in the journal Nature as a collaboration between some of the top research institutions and Mayo Clinic’s Center for Regenerative Medicine.

Mitochondrial diseases are a particular struggle for patients and their families as treatment options are limited, something made even more dire as many of those affected are children. Andre Terzic, M.D., Ph.D., director of Mayo Clinic’s Center

Andre Terzic, M.D., director, Mayo Clinic Center for Regenerative Medicine

Andre Terzic, M.D., director, Mayo Clinic Center for Regenerative Medicine

for Regenerative Medicine, explains: “These are life threatening conditions where standard care is limited to alleviating symptoms of disease. Our proof-of-concept study shows that functionally corrected stem cells can be generated from these patients, providing initial steps towards regenerative therapy for mitochondrial disease.”

Read the full post on the Center for Regenerative Medicine’s blog.

Tags: #FutureofHealthCare, Arizona, DNA mutations, Florida, Future of Health Care, Mayo Clinic, Mayo Clinic Center for Regenerative Medicine, Mayo Clinic Center for Regenerative Medicine, Minnesota, mitochondrial disease

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